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The weekend heralds the initial Wear-Tyne derby since 2024, but will it be – the Black Cats or Newcastle?
"Throughout the majority of last season, you couldn't have imagined the Wearside club rising to the top flight and challenging with Eddie Howe's Newcastle, let alone being above them in the table," remarked analyst Chris Sutton.
"Things are very different now, and the way Sunderland play leads me to believe they've got a genuine opportunity."
He is offering predictions for all 380 Premier League games this season, in competition with artificial intelligence, fans and a assortment of guests.
For this weekend's fixtures, he is challenged by England Gaming star Daniel 'Stingray' Ray.
Ray is vying for victory for the national gaming squad – the Football Association's formal esports team – at the football simulation digital Euros finals tournament, which will occur at Twickenham Stadium on Saturday.
The action will be streamed on Uefa's YouTube, Instagram Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and England's Twitch.
Do you agree with their predictions? Feel free to submit your own predictions below.
The fan-favourite scoreline selected for each game is displayed on the leaderboards at the bottom of this page.
A correct result (picking a win, draw or defeat) is worth ten points. A perfect prediction earns 40 points.
Ray, who also plays Gen City and Manchester City as well as England, is making his debut at the eEuros finals after successfully navigating the qualifying.
A group of eight will represent their nations at the finals in a straight knockout, playing for a substantial cash prize and a coveted spot in the FC Pro World Championship Play-Ins, with the Danish representative Anders Vejrgang defending the title he won last year.
"I am feeling really good for it," Ray remarked. "I have a really good coach by my side and training has been going well.
"It's always an honour to play for your country. Of course when you are younger, you imagine doing it as an professional footballer, but when you enter this profession and there is an chance to represent England, putting the shirt on is something incredible.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him over the course of the season just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"For me he is the number one in the world so defeating him in a tournament like this just provides a huge surge of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
Chelsea were impressive against the Gunners at the end of November, when they earned a stalemate after being reduced to 10 men, and I was thinking this is it, they could possibly be challengers for the crown.
However, since that game, however, they were beaten physically by Leeds, looked uninspired against Bournemouth and this week got turned over by Atalanta in the Champions League.
So boss Enzo Maresca is in need of a win here to restore momentum, but it will be a challenge because Everton are such a threatening team.
Their key midfielders are playing at the top of their game and Everton have got a bit of form at the moment.
On form you would probably back the visitors, while the most sensible prediction would likely be a draw, but I'm going against logic.
The Blues have failed to given me any compelling evidence to back them recently, but I just have a gut instinct Chelsea will emerge victorious because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'll be at this game and it will be interesting to see what we get from Liverpool.
I am really pleased for Reds boss Arne Slot to get such a important victory at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot ought not to put up with that nonsense. I know Salah has been a icon for the club but fundamentally Slot just wants to win games and there is nothing personal in his team selection.
They changed their tactical setup against Inter and went with a midfield diamond and two up top.
All the talk is going to be talking about whether Salah is included for this game, but the only way he is going to be brought back into the fold is if he apologises.
Slot's attention will be on winning this game, but it is a challenging encounter.
One might suggest it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are defensively susceptible too.
The Merseysiders need to get back to a consistent run of form, but I am not sure how much their energy spent at the San Siro will have affected their stamina.
I have whacked a couple of Brighton players in my Fantasy Premier League side, so they will likely do poorly - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the week off while Newcastle had to battle intensely against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
Apart from their brilliant performance against Everton a couple of weeks ago, Newcastle's away form has been poor, particularly straight after they've played in the Champions League.
I am expecting that pattern to continue on Sunday, and their tiredness is likely to be a key element in how this game goes because of their rivals' intensity.
We saw how relentless Regis le Bris's side are. They bullied the Gunners, and it was incredible to watch.
Everyone talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays alongside him, has also been one of the top transfers and deserves some attention too.
I am expecting this being the best game|most exciting fixture